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Lisa Kilpatrick, PhD
Assistant Researcher, Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA; Oppenheimer Center for Neurobiology of Stress
Lisa Kilpatrick’s research has focused on brain signatures related to brain-body dysregulation in stress-sensitive disorders, including irritable bowel syndrome. In addition, she has a long-standing interest in the influence of sex on these signatures, and she regularly attends and contributes to the annual meeting of the Organization for the Study of Sex Differences. The exploration of sex differences in the mechanisms of treatment response is an important step towards optimizing cost-effective treatments for both men and women. In her role as a co-Investigator in the Bioinformatics Core, she will apply her advanced expertise on the analysis of resting state fMRI data, as well as other neuroimaging modalities, to implement the proposed neuroimaging analyses. She maintains this expertise through regular attendance at the Biennial Resting State Conference and Organization for Human Brain Mapping annual meeting, and she can quickly adapt to new developments in the rapidly-changing field of neuroimaging. In addition, she will lend her expertise in sex differences during the interpretation of the findings. She has collaborated with Drs. Gupta, Labus, and Mayer over the years and looks forward to contributing to this ambitious project.
Publications
http://www.ncbi.nlm.nih.gov/myncbi/lisa.kilpatrick.1/bibliography/43276745/public/
Jason Kutch, PhD
Director, The Applied Mathematical Physiology Laboratory (AMPL); Associate Professor, Division of Biokinesiology and Physical Therapy, University of Southern California
Dr. Kutch’s laboratory is addressing the problem of chronic pelvic pain from a unique systems neuroscience perspective. He has a background in motor systems neuroscience, and have developed and published several non-invasive approaches to understanding muscle control in humans. They recently developed and published a new multimodal approach – including electromyography (EMG), functional magnetic resonance imaging (fMRI), and transcranial magnetic stimulation (TMS) – for revealing neural mechanisms of involuntary control of pelvic floor muscles. As the co-director of the neuroimaging working group in the NIDDK-funded multi-site Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network, he has played a leading role in the analysis of MAPP Phase I (2008-2013) fMRI data, and he currently plays a leading role in the design, implementation, and monitoring of the MAPP Phase II study (2014-2019). He leads MAPP research efforts to reveal brain imaging differences between pelvic pain patients and healthy controls, to predict longitudinal progression of pelvic pain symptoms from neuroimaging, and to stratify pelvic pain patients according to widespreadness of pain based on neuroimaging. In the proposed work, he will assist with the acquisition and analysis of novel 7T data to study sex related differences in patients with Irritable Bowel Syndrome (IBS).
http://www.ncbi.nlm.nih.gov/sites/myncbi/1B12ukyP87vQk/bibliography/47270130/public/