SCORE People

As Director of the UCLA Brain Tumor Imaging Laboratory and Co-Director of the UCLA Center for Computer Vision and Imaging Biomarkers (CVIB) his research focuses on the development, testing, validation, and implementation of advanced MR and PET imaging biomarkers for brain pathology and response evaluation in clinical trials. He possess a broad background in biomedical engineering, image processing, MR and PET imaging physics, functional and molecular imaging, bioelectronics, medical instrumentation, and statistical parameter mapping. He has been co-author on more than 100 peer-reviewed original research articles relating to advanced neuroimaging and medical imaging physics. He has wide-ranging experience in designing and implementing multicenter neuroimaging trials. This includes trials in primary and metastatic brain cancers; neurotrauma including traumatic brain injury (TBI), traumatic spinal cord injury (SCI), and degenerative spinal disease; psychiatric diseases including schizophrenia; epilepsy, tuberous sclerosis complex, and other neurodegenerative diseases; and chronic pain syndromes including cervical spondylotic myelopathy, irritable bowel syndrome (IBS), chronic headaches, and urological chronic pelvic pain syndrome (UCPPS). He is also the principal investigator for the imaging core in numerous industry-funded therapeutic clinical trials in brain tumors, chronic pain, epilepsy, and schizophrenia.
In this proposal, he will be Co-Lead of Project 2 and will be responsible for the design and analysis of all brainstem and brain MRI experiments, including optimization of protocols for both 3T and 7T imaging. His laboratory will post-process anatomic and diffusion MR imaging data, and work closely with Neuroimaging and Bioinformatics Core to identify sex-related differences in the brain and brainstem within IBS patients and the association with clinical symptoms and gut microbial parameters.

Publications

http://www.ncbi.nlm.nih.gov/sites/myncbi/1t5OXTmr85Skz/bibliography/50293169/public/