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Sex Differences in Anatomic Plasticity of Gut Neuronal – Mast Cell Interactions Luke A. Schwerdtfeger1 and Stuart A. Tobet1,2 1Department of Biomedical Sciences, 2School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado Background: Neural regulation of immune components throughout the gut wall has gained increased attention. Mucosal immune cells, like mast cells among others, […]

Sex-Specific Genetic Regulation of Adipose Mitochondria and Their Relationship to Metabolic Syndrome Karthickeyan Chella Krishnan1, Laurent Vergnes2, Linsey Stiles3, Lijiang Ma4, Rebeca Acín-Pérez3, Etienne Mouisel5, Calvin Pan1, Miklós Péterfy6, Karen Reue Vergnes2, Johan L.M. Björkegren4, Markku Laakso7, Aldons J. Lusis1,2,8  1Department of Medicine/Division of Cardiology, University of California, Los Angeles; 2Department of Human Genetics, University

Sex Differences in Neurophysiological Changes Following Voluntary Exercise in Adolescent Rats Lindsay Ferguson1,2, Christopher C. Giza1,2, Rebecka O. Serpa1,2, Tiffany Greco1,2, Hannah Roberts3, Michael Folkerts3, Mayumi L. Prins1,2. 1UCLA, David Geffen School of Medicine, Department of Neurosurgery, Brain Injury Research Center, Los Angeles, CA; 2UCLA, Steve Tisch BrainSPORT Program, Los Angeles, CA; 3Pepperdine University, Seaver

Dissecting Contributions of Prodromal Intestinal Inflammation to the Manifestation of Parkinson’s Disease Ping Fang, Lewis Yu, Hannah Espey, Yongning Deng, Hayley Hrncir, Arthur P. Arnold, Elaine Y. Hsiao Department of Integrative Biology & Physiology. University of California, Los Angeles. Los Angeles, CA 90095. Inflammation and immune dysregulation are increasingly implicated in the pathogenesis of Parkinson’s

Sex Differences in Fatty Acid and Mitochondrial Metabolism are Associated with Diastolic Dysfunction in Heart Failure Yang Cao1, Laurent Vergnes2,3, Calvin Pan1, Yuchen Wang1, Karthickeyan Chella Krishnan1, Timothy M. Moore1, Zhiqiang Zhou1, Sarada Charugundla1, Christoph Rau4, Marcus M. Seldin1, Jessica Wang1, Yibin Wang4, Karen Reue2,3,5, and Aldons J. Lusis1,2,6 1Division of Cardiology, Department of Medicine,

X-Linked Kdm5c Gene Dosage in Preadipocytes In Vivo Influences Adiposity and Food Intake Avetisyan1,2, L. Vergnes2, C.B. Wiese2, K. Reue1,2,3 1Molecular Cellular and Integrative Physiology, University of California, Los Angeles, Los Angeles, CA; 2Human Genetics, University of California, Los Angeles, Los Angeles, CA; 3David Geffen School of Medicine, University of California, Los Angeles, Los Angeles,

“Four Core Genotypes” Rats: Comparing Xx and Xy Rats with the Same Type of Gonads to Detect Sex Chromosome Effects That Cause Sex Differences in Physiology and Disease Arthur P. Arnold1, Xuqi Chen1, Michael Gryzbowski2, Lynn Lazcares2, Akiko Takizawa2, Laurent Vergnes3, Helen Skaletsky4, David C Page4, Karen Reue3, Melinda R. Dwinell2, and Aron M. Geurts2