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Integrated Multimodal Brain Signatures Predict Sex-Specific Obesity Status Ravi R. Bhatt*2, Newton Peng*1, Soumya Ravichandran1, Priten Vora1, Jean Stains1, Bruce Naliboff1, Emeran A. Mayer1, Arpana Gupta1  *Authors share co-first authorship 1G. Oppenheimer Center for Neurobiology of Stress and Resilience, Vatche and Tamar Manoukian Division of Digestive Disease, David Geffen School of Medicine at UCLA; 2Imaging […]

Sex-Related Cortical Alterations in Patients with Degenerative Cervical Myelopathy Talia Oughourlian1,2,3, Chencai Wang2,3, Noriko Salamon3, Langston T. Holly4, Benjamin M. Ellingson2,3,4,5 1Neuroscience Interdisciplinary Graduate Program, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; 2UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, David Geffen School

Do Adverse Childhood Experiences Influence Sensitivity to Side-effects and Reward Behavior on Hormonal Contraceptives? Andrew M. Novick MD PHD1, Joel Stoddard MD MAS1, Rachel L. Johnson MS2, Mary D. Sammel ScD1,2, and C. Neill Epperson MD1,3 1Department of Psychiatry, University of Colorado-Anschutz Medical Campus, Aurora, CO, USA; 2Department of Biostatistics and Informatics, Colorado School of

Sex-Specific Differences in Brainstem Microstructure in Chronic Visceral Pain Jennifer Labus, PhD1,2, Chencai Wang,PhD1,3, Priten Vora ,BS 1,2,  Cathy Liu, BS1,2, Jean Stains, RN,1,2,  Arpana Gupta,PhD,1,2  Emeran Mayer, MD,1,2  Ben Ellingson, PhD,1,3 1G. Oppenheimer Center for Neurobiology of Stress and Resilience, University of California Los Angeles; 2UCLA Vatche and Tamar Manoukian Division of Digestive Diseases,

Epigenetic Changes Associated with Sex and Their Role in Irritable Bowel Syndrome Pathophysiology Swapna Mahurkar-Joshi1-3, Elizabeth J Videlock2,3, Charalabos Pothoulakis2,3, Emeran A Mayer1-3, Lin Chang1-3 1G. Oppenheimer Center for Neurobiology of Stress and Resilience, 2Vatche and Tamar Manoukian Division of Digestive Diseases, 3David Geffen School of Medicine at UCLA Background: IBS is a female-predominant, stress-sensitive

Combined Oral Contraceptive Treatment Does Not Alter the Gut Microbiome or Serum Metabolomic Profile in Obese Girls with Polycystic Ovary Syndrome Beza Jobira1,2, Daniel N. Frank2, Lori J. Silveir3, Yesenia Garcia-Reyes1, Charles E. Robertson2, Diana Ir2, Keisha L Alexander5, Angelo D’Alessandro6, Kristen J. Nadeau1,4, and Melanie Cree-Green1,4 1Department of Pediatrics, Division of Pediatric Endocrinology, University

Longitudinal Changes in Liver Enzyme Levels Among Transgender People Receiving Gender Affirming Hormone Therapy Leila Hashemi, MD1,2, 3, Qi Zhang, MSPH4, Joseph Pisegna MD1,2, Michael Goodman MD, MPH 1VA Greater Los Angeles Healthcare System, Department of General Internal Medicine, Los Angeles, CA ; 2University of California Los Angeles, David Geffen School of Medicine, Los Angeles,

A Distinct Brain-Gut-Microbiome Profile Exists for Females with Obesity and Food Addiction Tien S. Dong1-3,5, Emeran A. Mayer1-5, Vadim Osadchiy,4,5 Candace Chang3, William Katzka3, Venu Lagishetty1,3,5, Kimberly Gonzalez1,4,5, Amir Kalani1,5, Jean Stains1,4,5, Jonathan P. Jacobs1-6, Valter D. Longo7, Arpana Gupta1-5 1Vatche and Tamar Manoukian Division of Digestive Diseases, 2David Geffen School of Medicine, 3UCLA Microbiome

The Impact of Biological Sex and Circulating Sex Hormones on Oxidative Stress: Implications for Neural Regulation of Obesity Jessica N. Buslera,b, Sarah Rose Slatea, Eduardo Coelloa, Vicky Liaoa, Alexander P. Lina, Pamela B. Mahona aReproductive Outcomes of Stress and Aging (ROSA) Center, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA, USA; bHarvard T. H.

Kdm5c Gene Dosage Determines Sex Differences in Adiposity Carrie B. Wiese,1 Jenny C. Link,2 Xuqi Chen,3 Rozeta Avetisyan,1 Emilio Ronquillo,1 Feiyang Ma,4 Julia S. El-Sayed Moustafa,5 Kerrin S. Small,5 Matteo Pellegrini,4 Laurent Vergnes,1 Arthur P. Arnold,3 and Karen Reue1 1Department of Human Genetics, UCLA, 2Molecular Biology Institute, UCLA, 3Integrative Biology and Physiology, UCLA, 4Department of