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Sex Differences in the Neural Control of Energy Balance

Stephanie Correa, PhD Assistant Professor, Integrative Biology and Physiology, UCLA Financial Disclosure: None Members of the Correa Lab are interested in understanding how basic homeostatic functions are modulated by sex variables. Our research focuses on the effects of estrogens on thermoregulation and energy balance in mice, with a goal to understand the hot flashes and …

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Sex, Mitochondria and Fat Metabolism

Karthickeyan Chella Krishnan, PhD Assistant Professor, Pharmacology and Systems Physiology, University of Cincinnati College of Medicine Financial Disclosure: None Background and Objectives: Mitochondria plays a major role in the pathophysiology of complex metabolic traits such as obesity, insulin resistance and fatty liver disease. However, the exact causal relationship between mitochondrial function and these traits is …

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Brain-Gut-Microbiome Sex Differences in Food Addiction

Tien Dong, MD, PhD Assistant Professor, Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA Financial Disclosure: None Alterations in brain-gut-microbiome interactions have been implicated as an important factor in obesity. We aimed to explore the relationship between food addiction (FA) and the brain-gut-microbiome axis using a multi’omics approach …

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Epigenetic Changes Associated with Sex and Their Role in Irritable Bowel Syndrome Pathophysiology

Swapna Joshi, PhD Adjunct Assistant Professor, G. Oppenheimer Center for Neurobiology of Stress and Resilience and Center for Systems Biomedicine, Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA Financial Disclosure: None IBS is a female-predominant, stress-sensitive disorder with increased prevalence of early adverse life events (EALs). EALs may …

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Sex Differences in the Cardiovascular Consequences of Type 2 Diabetes

Judith G. Regensteiner, PhD Director, Center for Women’s Health Research, Professor of Medicine, Divisions of Internal Medicine and Cardiology, University of Colorado Denver Financial Disclosure: None Type 2 diabetes (T2D) is associated with increased morbidity and mortality, primarily due to cardiovascular disease (CVD) in both women and men. Among nondiabetic individuals, absolute rates of CVD …

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Central And Peripheral Mechanisms Associated with Maintenance and Production of Symptoms in Provoked Vestibulodynia

Andrea Rapkin, MD Professor, Department of Obstetrics and Gynecology, UCLA Financial Disclosure: None Jennifer Labus PhD Director, Biostatistics and Bioinformatics Core, G. Oppenheimer Center for Neurobiology of Stress and Resilience; Adjunct Professor, Vatche and Tamar Manoukian Division of Digestive Diseases, UCLA Financial Disclosure: None The most prevalent subtype of vulvodynia, provoked vestibulodynia (PVD), is a …

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