SCOR Publications (2012 – Present)


Chen X, Wang L LohD, Colwell CS, Tache Y, Reue R, Arnold AP. Sex differences in diurnal rhythms of food intake in mice caused by gonadal hormones a nd complement of sex chromosomes. Horm Behav. 2015 Jul 29;75:55-63. [Epub ahead of print]

Coveleskie K, Gupta A, Labus JS, Mayer ED, Ashe-McNalley C, Stains J, Kilpatrick LA, Mayer EA. Altered Functional Connectivity within the Central Reward Network in Overweight and Obese Women. Nutr Diabetes. 2015 Jan 19;5:e148. PMCID: PMC4314578

Gupta A, Labus JS, Kilpatrick L, Bonyadi M, Ashe-McNalley C, Heendeniya N, Bradesi S, Chang L, Mayer EA. Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain Struct Funct. 2015 Jan 30. [Epub ahead of print]. PMCID: PMC4573367 [Available on 2016-07-30]

Gupta A, Rapkin AJ, Gill, Z, Kilpatrick LA, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. Disease-Related Differences in Resting State Networks: A Comparison Between Localized Provoked Vulvodynia, Irritable Bowel Syndrome, and Healthy Control Subjects. Pain. 2015 May;156(5):809-19. PMCID: PMC4402252.[Available on 2016-05-01]

*Gupta A, *Orand A, Shih W, Presson AP, Hammer C, Niesler B, Heendeniya N, Mayer EA, Chang L. Catecholaminergic Gene Polymorphisms are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PLoS One. 2015 Aug 19;10(8):e0135910. PMCID: PMC4546052

Guo Y, Wang Z, Mayer EA, Holschneider DP. Neonatal stress from limited bedding elicits visceral hyperalgesia in adult rats. Neuroreport. 2015 Jan 7;26(1):13-6. PMCID: PMC4246414 [Available on 2016-01-07]

Hong JY, Kilpatrick L, Labus JS, Gupta A, Katibian D, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Naliboff B, Mayer EA. Sex and Disease-Related Alterations of Anterior Insula Functional Connectivity in Chronic Abdominal Pain. J. Neuroscience, 2015. 34(43):14252-9. PMCID: PMC4205551

Hubbard CS, Hong J, Jiang Z, Ebrat B, Suyenobu B, Smith S, Heendeniya N, Naliboff BD, Tillisch K, Mayer EA, Labus JS. Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterol Motil. 2015 Sep;27(9):1282-94. PMCID: PMC4550526.

*Kilpatrick LA, *Mayer EA, Labus JS, Gupta A, Hamaguchi T, Mizuno T, Komuro H, Kano M, Kanazawa M, Aoki M, Fukudo S. Seretonin transporter gene polymorphism modulates activity and connectivity within an emotional arousal network of healthy men during an aversive visceral stimulus. PLoS One. 2015 Apr 20;10(4):e0123183. PMCID: PMC4404144.

Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict chronic abdominal pain patients from healthy control subjects. Pain. 2015. 156(8): 1545-54. PMCID: PMC4504800.

Mayer EA, Tillisch K, Gupta A. Gut-Brain Axis and the Microbiota. Journal of Clinical Investigation. 2015; 125(3): 926-38.[Epub ahead of Print]. PMCID: PMC4362231 [Available on 2016-03-02]

Mayer EA, Gupta A, Kilpatrick L, Hong JY. Imaging brain mechanisms in Visceral Pain-Review. Pain. 2015 Apr;156 Suppl 1:S50-63. PMCID: PMC4428597 [Available on 2016-04-01]

Sideri A, Stavrakis D, Bowe C, Shih DQ, Fleshner P, Arsenescu V, Arsenescu R,Turner JR, Pothoulakis C, Karagiannides I. Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. Am J Physiol Gastrointest Liver Physiol. 2015 Apr 1;308(7):G591-604. PMCID: PMC4385897.

Taché Y. Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. Neurogastroenterol Motil. 2015 Jan;27(1):1-6. Review

Taché Y and Million M. Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia. J Neurogastroenterol Motil. 2015 Jan 31;21(1):8-24. PMCID: PMC4288101


Gupta A, Kilpatrick L, Labus J, Tillisch K, Braun A, Hong JY, Ashe-McNalley C, Naliboff B, Mayer EA. Early Adverse Life Events: Influence on Resting State Scans in Male and Female Patients with Chronic Abdominal Pain. Psychosomatic Medicine. 2014; 76(6):404-12. PMCID: PMC4113723.

Hong JY, Kilpatrick LA, Labus JS, Gupta A, Katibian D, Ashe-McNalley C, Stains J, Heendeniya N, Smith S, Tillisch K, Naliboff B, Mayer EA. Sex and Disease-Related Alterations of Anterior Insula Functional Connectivity in Chronic Abdominal Pain. Journal of Neuroscience. 2014; 34(43):14252-9. PMCID: PMC4205551

Kilpatrick LA, Coveleskie K, Connolly L, Labus JS, Ebrat B, Stains J, Jiang Z, Suyenobu BY, Raybould HE, Tillisch K, Mayer EA. Influence of Sucrose Ingestion on Brainstem and Hypothalamic Intrinsic Oscillations in Lean and Obese Women. Gastroenterology 2014, 146(5) 1212-21. PMCID: PMC4113508

Kilpatrick LA, Kutch JJ, Tillisch K, Naliboff BD, Labus JS, Jiang Z, Farmer M, Apkarian AV, Mackey S, Martucci KT, Clauw D, Harris RE, Deutsch G, Ness T, Yang CC, Maravilla K, Mullins C, Mayer EA. Alterations in resting state oscillations and connectivity within sensory and motor networks in women with interstitial cystitis/painful bladder syndrome. Journal of Urology 2014; 192(3):947-55. PMCID: PMC4432915

Mulak A, Taché Y. Larauche M. Sex hormones in the modulation of irritable bowel syndrome. World J Gastro 2014 20:2433-2448. PMCID: PMC3949254

Petersen N, Kilpatrick LA, Goharzad A, Cahill L. Oral contraceptive pill use and menstrual cycle phase are associated with altered resting state functional connectivity. Neuroimage (2014). Apr 15;90:24-32. PMCID: PMC4113343

Su A, Shih W, Presson AP, Chang L. Characterization of symptoms in irritable bowel syndrome with mixed bowel habit pattern. Neurogastroenterology and Motility 2014;26(1):36-45. PMCID: PMC3865067

Karagiannides I, Golovatscka V, Bakirtzi K, Sideri A, Stavrakis D, Polytarchou C, Iliopoulos D, Pothoulakis C, and Bradesi S. Chronic unpredictable stress regulates visceral adipocyte-mediated glucose metabolism and inflammatory circuits in male rats. Physiol Rep. 2014 May 12;2(5):e00284. PMCID: PMC4098730


Cheng P, Alberto M, Shih W, Presson AP, Licudine A, Mayer EA, Naliboff BD, Chang L. Autonomic response to a visceral stressor is dysregulated in irritable bowel syndrome and correlates with visceral perception. Neurogastroenterology and Motility 2013;25(10):e650-9. PMCID: PMC3788031

Grasberger H, Chang L, Shih W, Presson AP, Karagiannides I, Pothoulakis C, Mayer EA, Merchant JL. Identification of a Functional TPH1 Polymorphism Associated with Irritable Bowel Syndrome Bowel Habit Subtypes. American Journal of Gastroenterology 2013 Nov;108(11):1766-74. PMCID: PMC4067697

Kim SE, Chang L. Overlap between functional GI disorders and other functional syndromes: What are the underlying mechanisms? Neurogastroenterology and Motility 2012;24(10):895-913. PMCID: PMC3812246

Connolly L, Coveleskie K, Kilpatrick LA, Labus JS, Ebrat B, Stains J, Jiang Z, Tillisch K, Raybould HE, Mayer EA. Differences in brain responses between lean and obese women to a sweetened drink. Neurogastroenterol Motil. 2013 Jul;25(7):579-e460. PMCID: PMC4114731

Wang Z, Ocampo MA, Pang RD, Bota M, Bradesi S, Mayer EA, Holschneider DP. Impaired Alterations in Prefrontal-Limbic Functional Activation and Connectivity in Chronic Stress-Induced Visceral Hyperalgesia. PLoS ONE, 8(3):e59138, 2013. PMCID: PMC3602545.

Chatzaki E, Anton PA, Million M, Lambropoulou M, Costantinidis T, Kolios G, Taché Y, and Grigoriadis DE. Corticotropin-releasing factor receptor subtype 2 in human colonic mucosa: Down-regulation in ulcerative colitis. World J Gastro 19:1416-1423, 2013. PMCID: PMC3602501.

Ellingson BM, Mayer EA, Harris RJ, Ashe-McNalley C, Naliboff BD, Labus JS, Tillisch K. Diffusion tensor imaging detects microstructural reorganization in the brain associated with chronic irritable bowel syndrome. Pain 2013 Apr 8. pii: S0304-3959(13)00165-6. doi: 10.1016/j.pain.2013.04.010. PMCID: PMC3758125

Hong J-Y, Kilpatrick L, Labus JS, Gupta A, Jiang Z, Ashe-McNalley C, Stains J, Heendeniya N, Ebrat B, Smith S, Tillisch K, Naliboff B, Mayer EA. Patients with Chronic Visceral Pain Show Sex-Related Alterations in Intrinsic Oscillations of the Resting Brain. J. Neurosci 33(29):11994-12002, 2013. PMCID: PMC3713732

Jiang Z, Dino ID, Labus J, Shi Y, Zamanyan A, Gupta A, Ashe-McNalley C, Hong JY, Tillisch K, Toga AW, Mayer EA.. Sex-Related Differences of Cortical Thickness in Patients with Chronic Abdominal Pain. PLOS ONE, 2013. PMCID: PMC3764047

Labus JS, Jian Z, Dinov I, Ashe-McNalley C, Zamanyan A, Shi Y, Hong J-Y, Gupta A, Ebrat B, Tillisch K, Hobel S, Gutman B, Joshi S, Thompson PM, Toga AW, Mayer EA. Irritable Bowel Syndrome in Female Patients Is Associated with Alterations in Structural Brain Networks. Pain 2013. 155(1), 137-149. PMCID: PMC4100785

Labus JS, Gupta A, Coveleskie K, Tillisch K, Kilpatrick L, Jarcho J, Feier N, Bueller J, Stains J, Smith S. Suyenobu B, Naliboff BN, Mayer EA. Sex Differences in Emotion-related Cognitive Processes in Irritable Bowel Syndrome and Healthy Control Subjects. Pain, 2013 Jun 20. pii:S0304-3959(13)00332-1. doi: 10.1016/j.pain.2013.06.024. PMCID: PMC4049231

Yuan PQ, Wu SV, Elliott J, Anton PA, Chatzaki E, Million M, Taché Y. Expression of corticotropin releasing factor receptor type 1 (CRF(1) in the human gastrointestinal tract and upregulation in the colonic mucosa in patients with ulcerative colitis. Peptides. 38:62-69, 2012. PMCID: PMC3652978

Million M, Zhao J-F, Luckey , Czimmer J, Maynard JD, Kehne J, Hoffman DC Taché Y. The newly developed CRF1-receptor antagonists, NGD 98-2 and NGD 9002, suppress acute stress-induced stimulation of colonic motor function and visceral hypersensitivity in rats. 2013 Sep 6;8(9):e73749. PMCID: PMC3765344

Kashyap PC, Marcobal A, Ursell LK, Larauche M, Duboc H, Earle KA, Sonnenburg ED, Ferreyra JA, Higginbottom SK, Million M, Taché Y, Pasricha PJ, Knight R, Farrugia G, Sonnenburg JL. Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice. Gastroenterology 2013 May;144(5):967-77. PMCID: PMC3890323


Berman S, Suyenobu B, Naliboff BD, Bueller J, Stains J, Wong H, Mandelkern M, Fitzgerald L, Ohning G, Gupta A, Labus JS, Tillisch K, Mayer EA. Evidence for alterations in central noradrenergic signaling in irritable bowel syndrome. Neuroimage. 2012 Dec;63(4):1854-63. PMCID: PMC4130741

Bradford K, Shih W, Videlock E, Presson AP, Naliboff BD, Mayer EA, Chang L. Association of early adverse life events and irritable bowel syndrome. Clinical Gastroenterology and Hepatology 2012;10(4):385-390. PMCID: PMC3311761

Chang L, Adeyemo M, Karagiannides I, Videlock EJ, Bowe C, Shih W, Presson AA, Yuan PQ, Gong H, Singh S, Cortina G, Licudine A, Tache Y, Pothoulakis C, Mayer EA. Serum and colonic immune markers in irritable bowel syndrome. American Journal of Gastroenterology 2012; 107(2):262-72. PMCID: PMC3311761

Chang L. Invited review: The role of stress on physiologic responses and clinical symptoms in IBS. Gastroenterology 2011;140(3):761-765. PMCID: PMC3039211

Kilpatrick LA and Tillisch K (2012). Irritable bowel syndrome. Handbook of Gender Medicine. Eds: Schenck-Gustafsson K, DeCola PR, Pfaff DW, Pisetsky DS. Karger, Basel.

Kim SE, Chang L. Overlap between functional GI disorders and other functional syndromes: What are the underlying mechanisms? Neurogastroenterology and Motility 2012 Oct;24(10):895-913. PMCID: PMC3812246

Larauche M, Mulak A, Kim YS, Labus J, Million M, Taché Y. Visceral analgesia induced by acute and repeated water avoidance stress in rats: sex difference in opioid involvement. Neurogastroenterol Motil. 2012 Nov;24(11):1031-e547. PMCID: PMC3470786

Larauche M, Mulak A and Taché Y. Stress and visceral pain: From animal models to clinical therapies. Exp Neurol. 2012 Jan;233(1):49-67. PMCID: PMC3224675

Mulak A, Larauche and Taché Y. Modulation of visceral pain by stress: implication in irritable bowel syndrome. In Current Concepts in Colonic Disorders. (ed) Godfrey Lule. 2012, 251-260.

Mulak A, Larauche M and Taché. Psychological stress induced visceral analgesic or hyperalgesic response in rodents. A role of preconditions. Front Gastrointest Res. 2012;30:106-114. PMCID: PMC4231824

Naliboff BD, Kim S, Bolus R, Bernstein CN, Mayer EA, Chang L. Gastrointestinal and Psychological Mediators of Health Related Quality of Life in IBS and IBD: A Structural Equation Modeling Analysis. Am J Gastroenterol. 2012 Mar;107(3):451-9. PMCID: PMC3855477

Yuan PQ, Wu SV, Elliott J, Anton PA, Chatzaki E, Million M, Taché Y. Expression of corticotropin releasing factor receptor type 1 (CRF(1) in the human gastrointestinal tract and upregulation in the colonic mucosa in patients with ulcerative colitis. Peptides. 2012 Nov;38(1):62-9. PMCID: PMC3652978

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